R162
Cat. No.：YN480237
CAS No. ：64302-87-0
规格
价格(RMB)
库存
| 产品名称: | R162 |
| CAS No.: | 64302-87-0 |
| Chemical Name: | 1-hydroxy-2-(2-propen-1-yl)-9,10-anthracenedione |
| Synonyms: | R162,R-162,R 162 |
| 分子量: | 264.28 |
| 分子式: | C₁₇H₁₂O₃ |
| SMILES: | O=C1C2=C(C=CC=C2)C(C3=CC=C(CC=C)C(O)=C13)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | R162 是一种有效的谷氨酸脱氢酶 (GDH1/GLUD1) 抑制剂，具有抗癌的作用。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Jin, L., Li., D., Alesi, G.N., et al.Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growthCancer Cell27(2),257-270(2015)
Jin, L., Chun, J., Pan, C., et al.The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CamKK2-AMPK signaling in LKB1-deficient lung cancerMol. Cell69(1),87-99(2018)
