KH7
Cat. No.：YN480238
CAS No. ：330676-02-3
规格
价格(RMB)
库存
| 产品名称: | KH7 |
| CAS No.: | 330676-02-3 |
| Chemical Name: | 2-(1H-benzimidazol-2-ylthio)-2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide, propanoic acid |
| Synonyms: | (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;KH 7;2-(1H-benzimidazol-2-ylsulfanyl)-N'-[(Z)-(3-bromo-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]propanehydrazide;AC1OBAO2;AGN-PC-005XAZ;CTK8E6712;(E)-2-(1H-Benzo[ |
| 分子量: | 419.30 |
| 分子式: | C₁₇H₁₅BrN₄O₂S |
| SMILES: | CC(SC1=NC2=CC=CC=C2N1)C(N/N=C/C3=CC(Br)=CC=C3O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KH7 是一种可溶性腺苷酸环化酶(sAC)的特异性抑制剂，其在细胞中测得对重组sACt蛋白 (人源和其它) 的IC50值为 3-10 μM。KH7 也是cAMP的抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Wuttke, M.S., Buck, J., and Levin, L.R.Bicarbonate-regulated soluble adenylyl cyclaseJOP2(4 Suppl),154-158(2001)
Hess, K.C., Jones, B.H., Marquez, B., et al.The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilizationDev. Cell9(2),249-259(2005)
Hallows, K.R., Wang, H., Edinger, R.S., et al.Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cellsJ. Biol. Chem.284(9),5774-5783(2009)
Kumar, S., Kostin, S., Flacke, J.P., et al.Soluble adenylyl cyclase controls mitochondria-dependent apoptosis in coronary endothelial cellsJ. Biol. Chem.284(22),14760-14768(2009)
