DSP-4 hydrochloride
Cat. No.：YN480239
CAS No. ：40616-75-9
规格
价格(RMB)
库存
| 产品名称: | DSP-4 hydrochloride |
| CAS No.: | 40616-75-9 |
| Chemical Name: | 2-bromo-N-(2-chloroethyl)-N-ethyl-benzenemethanamine, monohydrochloride |
| Synonyms: | Neurotoxin DSP 4 (hydrochloride) |
| 分子量: | 313.06 |
| 分子式: | C₁₁H₁₆BrCl₂N |
| SMILES: | CCN(CCCl)CC1=CC=CC=C1Br.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) 是一种高选择性的神经毒素，容易通过血脑屏障，对成年和发育中大鼠去甲肾上腺素能神经元具有神经毒性作用，可用于中枢和外周去甲肾上腺素能神经元的暂时选择性降解，主要是来自蓝斑 (LC) 的神经元。 |
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Jaim-Etcheverry, G., and Zieher, L.M.DSP-4: A novel compound with neurotoxic effects on noradrenergic neurons of adult and developing ratsBrain Res.188(2),513-523(1980)
Grzanna, R., Berger, U., Fritschy, J.M., et al.Acute action of DSP-4 on central norepinephrine axons: Biochemical and immunohistochemical evidence for differential effectsJ. Histochem. Cytochem.37(9),1435-1442(1989)
Rajabi, S., Shamsizadeh, A., Amini, H., et al.Effect of DSP-4 induced central noradrenergic depletion on tactile learning in ratNeurol. Res.34(1),80-84(2012)
Harro, J., Oreland, L., Vasar, E., et al.Impaired exploratory behaviour after DSP-4 treatment in rats: Implications for the increased anxiety after noradrenergic denervationEur. Neuropsychopharmacol.5(4),447-455(1995)
