Pimonidazole
Cat. No.:YN480274
产品名称: | Pimonidazole |
CAS No.: | 70132-50-2 |
Chemical Name: | α-[(2-nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol |
Synonyms: | 哌莫硝唑 |
分子量: | 254.29 |
分子式: | C₁₁H₁₈N₄O₃ |
SMILES: | OC(CN1C=CN=C1[N+]([O-])=O)CN2CCCCC2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pimonidazole 是一种缺氧标记物,用于瘤内缺氧和细胞增殖的补充性研究。Pimonidazole 通过与大分子的共价结合或通过被还原形成还原性代谢物后在缺氧细胞中积累,可用于定性和定量评估肿瘤缺氧。 |
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Kaanders, J.H.A.M., Wijffels, K.I.E.M., Marres, H.A.M., et al.Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancerCancer Res.62(23),7066-7074(2002)