Arundic Acid
Cat. No.：YN480336
CAS No. ：185517-21-9
规格
价格(RMB)
库存
| 产品名称: | Arundic Acid |
| CAS No.: | 185517-21-9 |
| Chemical Name: | 2R-propyl-octanoic acid |
| Synonyms: | ONO-2506; (R)-2-Propyloctanoic acid |
| 分子量: | 186.29 |
| 分子式: | C₁₁H₂₂O₂ |
| SMILES: | CCCCCC[C@H](C(O)=O)CCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Arundic acid (ONO-2506) 是一种星形胶质细胞调节剂，通过抑制 S-100β 的合成，调节星形胶质细胞的活化来延缓脑梗塞的扩张。 Arundic acid (ONO-2506) 有潜力用于中风和阿尔茨海默病的研究。 |
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Tateishi, N., Mori, T., Kagamiishi, Y., et al.Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: Suppression of astrocytic activation by a novel agent (R)-(–)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficitsJ. Cereb. Blood Flow Metab.22(6),723-734(2002)
Kato, H., Kurosaki, R., Oki, C., et al.Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in miceBrain Res.1030(1),66-73(2004)
