PF-9366
Cat. No.:YN480338
产品名称: | PF-9366 |
CAS No.: | 72882-78-1 |
Chemical Name: | 7-chloro-N,N-dimethyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinoline-1-ethanamine |
Synonyms: | PF-9366; PF 9366; PF9366,72882-78-1 |
分子量: | 350.84 |
分子式: | C₂₀H₁₉ClN₄ |
SMILES: | CN(C)CCC1=NN=C2N1C3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PF-9366 是一种有效的甲硫氨酸腺苷转移酶 (Mat2A) 抑制剂,IC50值和Kd值分别为 420 nM 和 170 nM。 |
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Quinlan, C.L., Kaiser, S.E., Bolaños, B., et al.Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2ANat. Chem. Biol.13(7),785-792(2017)