UNC3230
Cat. No.:YN480432
产品名称: | UNC3230 |
CAS No.: | 1031602-63-7 |
Chemical Name: | 5-[(cyclohexylcarbonyl)amino]-2-(phenylamino)-4-thiazolecarboxamide |
Synonyms: | UNC 3230 |
分子量: | 344.43 |
分子式: | C₁₇H₂₀N₄O₂S |
SMILES: | O=C(C1=C(NC(C2CCCCC2)=O)SC(NC3=CC=CC=C3)=N1)N |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | UNC3230 是一种有效的选择性的,ATP 竞争性的磷脂酰肌醇 4 磷酸 5 激酶 1C 型 (PIP5K1C) 抑制剂,IC50约为 41 nM。UNC3230 还可抑制PIP4K2C,但不抑制其他调节磷酸肌醇水平的脂质激酶。UNC3230 具有镇痛和抗癌作用。 |
IC50和靶点: | |
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Wright, B.D., Loo, L., Street, S.E., et al.The lipid kinase PIP5K1C regulates pain signaling and sensitizationNeuron82(4),836-847(2014)