Tilfrinib
Cat. No.：YN480438
CAS No. ：1600515-49-8
规格
价格(RMB)
库存
| 产品名称: | Tilfrinib |
| CAS No.: | 1600515-49-8 |
| Chemical Name: | 3-(9H-pyrido[2,3-b]indol-4-ylamino)-phenol |
| Synonyms: | |
| 分子量: | 275.30 |
| 分子式: | C₁₇H₁₃N₃O |
| SMILES: | OC1=CC=CC(NC2=C3C4=CC=CC=C4NC3=NC=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tilfrinib (compound 4f) 是一种高效、选择性的Brk抑制剂，IC50值为 3.15 nM，具有抗增殖活性，有前景成为抗肿瘤药物。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Mahmoud, K.A., Krug, M., Wersig, T., et al.Discovery of 4-anilino α-carbolines as novel Brk inhibitorsBioorg. Med. Chem. Lett.24(8),1948-1951(2014)
Mahmoud, K.A., Wersig, T., Slynko, I., et al.Novel inhibitors of breast cancer relevant kinases Brk and HER2Med. Chem. Commun.5,659-664(2014)
