Bragsin1
Cat. No.:YN480467
产品名称: | Bragsin1 |
CAS No.: | 369631-68-5 |
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分子量: | 273.16 |
分子式: | C₁₁H₆F₃NO₄ |
SMILES: | O=C1C=C(C(F)(F)F)OC2=CC=C(C)C([N+]([O-])=O)=C21 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bragsin1 是一种有效、选择性、非竞争性的核苷酸交换因子ArfGEF BRAG2抑制剂,抑制 Arf GTPase 活化,IC50值为 3 μM。Bragsin1 与 BRAG2 的 PH 结构域结合,为非竞争性界面抑制剂,对人 ArfGEFs 的 Sec7 结构域无作用。具有抗肿瘤活性。 |
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