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N6-Methyladenosine 5'-monophosphate disodium salt

Cat. No.:YN480490

  • CAS No. :81921-35-9

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    • 产品名称: N6-Methyladenosine 5'-monophosphate disodium salt
      CAS No.: 81921-35-9
      Chemical Name: N-methyl-5'-adenylic acid, disodium salt
      Synonyms:
      分子量:405.21
      分子式:C₁₁H₁₄N₅Na₂O₇P
      SMILES:CNC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(O[Na])(O[Na])=O)O3)C=N2)=NC=N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: N6-Methyladenosine 5'-monophosphate disodium salt 是糖原磷酸化酶b的激活剂,Ka值为22 µM。N6-Methyladenosine 5'-monophosphate disodium salt 也是腺苷酸激酶II 的抑制剂。
      IC50和靶点:
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    • Morange, M., García Blanco, F., Vandenbunder, B., et al.AMP Analogs : Their function in the activation of glycogen phosphorylase bEur. J. Biochem.65(2),553-563(1976)

      Hai, T.T., Picker, D., Abo, M., et al.Species- or isozyme-specific enzyme inhibitors. 7. Selective effects in inhibitions of rat adenylate kinase isozymes by adenosine 5’-phosphate derivativesJ. Med. Chem.25(7),806-812(1982)

      Fry, N.J., Law, B.A., Ilkayeva, O.R., et al.N6-methyladenosine is required for the hypoxic stabilization of specific mRNAsRNA23(9),1444-1455(2017)

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