Menaquinone-7
Cat. No.：YN480535
CAS No. ：2124-57-4
规格
价格(RMB)
库存
| 产品名称: | Menaquinone-7 |
| CAS No.: | 2124-57-4 |
| Chemical Name: | 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaen-1-yl]-3-methyl-1,4-naphthalenedione |
| Synonyms: | Vitamin K2-7; Vitamin K2(35); Vitamin MK-7 |
| 分子量: | 649.00 |
| 分子式: | C₄₆H₆₄O₂ |
| SMILES: | O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(C)C(C2=C1C=CC=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Menaquinone-7 (Vitamin K2-7) 是维生素K2家族的成员，最早作为抗出血因子被发现。Menaquinone-7 (Vitamin K2-7)是Gla-蛋白羧化反应中最具生物活性的辅因子。补充Menaquinone-7 (Vitamin K2-7) 也是激活Gla基质蛋白并干预钙化性主动脉瓣狭窄(CAVS)进展的一种药理选择。 |
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Katsuyama, H., Otsuki, T., Tomita, M., et al.Menaquinone-7 regulates the expressions of osteocalcin, OPG, RANKL and RANK in osteoblastic MC3T3E1 cellsInt. J. Mol. Med.15(2),231-236(2005)
Ehara, Y., Takahashi, H., Hanahisa, Y., et al.Effect of vitamin K2 (menaquinone-7) on bone metabolism in the femoral-metaphyseal tissues of normal and skeletal-unloaded rats: Enhancement with zincRes. Exp. Med. (Berl.)196(3),171-178(1996)
Scheiber, D., Veulemans, V., Horn, P., et al.High-dose menaquinone-7 supplementation reduces cardiovascular calcification in a murine model of extraosseous calcificationNutrients7(8),6991-7011(2015)
Wu, W.-J., Lee, H.-Y., Lee, G.-H., et al.The antiosteoporotic effects of Cheonggukjang containing vitamin K2 (menaquinone-7) in ovariectomized ratsJ. Med. Food17(12),1298-1305(2014)
