5-Chloro-2'-deoxyuridine
Cat. No.:YN480549
产品名称: | 5-Chloro-2'-deoxyuridine |
CAS No.: | 50-90-8 |
Chemical Name: | 5-chloro-2'-deoxy-uridine |
Synonyms: | 5-Chlorodeoxyuridine; CldU |
分子量: | 262.65 |
分子式: | C₉H₁₁ClN₂O₅ |
SMILES: | OC[C@@H]1[C@H](C[C@H](N2C(NC(C(Cl)=C2)=O)=O)O1)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 5-Chloro-2'-deoxyuridine,一个胸腺嘧啶的类似物,可用于研究次氯酸对 DNA 和 DNA 前体的破坏作用。 |
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Patra, A., Harp, J., Pallan, P.S., et al.Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairsNucleic Acids Res.41(4),2689-2697(2012)
Yuan, C.J., Quiocho, J.M.D., Kim, A., et al.Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cyclePharmacol. Biochem. Behav.100(1),98-108(2011)
Anda, S., Boye, E., and Grallert, B.Cell-cycle analyses using thymidine analogues in fission yeastPLoS One9(2),1-9(2014)
Llorens-Martín, M., Tejeda, G.S., and Trejo, J.L.Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: A sueal birthdating analysisPLoS One5(8),1-15(2010)
Tuttle, A.H., Rankin, M.M., Teta, M., et al.Immunofluorescent detection of two thymidine analogues (CldU and IdU) in primary tissueJ. Vis. Exp.7(46),2-5(2010)
Fox, L.M., Mekras, J.A., Bagwell, C.B., et al.Capacity of deoxycytidine to selectively antagonize cytotoxicity of 5-halogenated analogs of deoxycytidine without loss of antiherpetic activityAntimicrob. Agents Chemother.22(3),431-441(1982)