FDI-6
Cat. No.:YN480556
产品名称: | FDI-6 |
CAS No.: | 313380-27-7 |
Chemical Name: | 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)-thieno[2,3-b]pyridine-2-carboxamide |
Synonyms: | NCGC00099374 |
分子量: | 437.43 |
分子式: | C₁₉H₁₁F₄N₃OS₂ |
SMILES: | O=C(C1=C(N)C2=C(C(F)(F)F)C=C(C3=CC=CS3)N=C2S1)NC4=CC=C(F)C=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | FDI-6 是一种FOXM1抑制剂。作用于 MCF-7 乳腺癌细胞中,FDI-6 直接与 FOXM1 蛋白结合,从靶基因组中取代 FOXM1,并诱导随后的转录下调。 |
IC50和靶点: | |
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Solvent & Solubility: |
Gormally, M.V., Dexheimer, T.S., Marsico, G., et al.Suppression of the FOXM1 transcriptional programme via novel small molecule inhibitionNat. Commun.5,5165(2014)