Thromboxane B2
Cat. No.:YN480584
产品名称: | Thromboxane B2 |
CAS No.: | 54397-85-2 |
Chemical Name: | 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid |
Synonyms: | |
分子量: | 370.48 |
分子式: | C₂₀H₃₄O₆ |
SMILES: | O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C[C@@H]1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. |
IC50和靶点: | |
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Needleman, P., Moncada, S., Bunting, S., et al.Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxidesNature261(5561),558-560(1976)
Patrono, C., Ciabattoni, G., Pugliese, F., et al.Estimated rate of thromboxane secretion into the circulation of normal humansJ. Clin. Invest.77(2),590-594(1986)
Uyama, O., Matsumoto, M., Fujisawa, A., et al.Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular diseaseProstaglandins Med.7(3),199-207(1981)
Arantes, F.B.B., Menezes, F.R., Franci, A., et al.Influence of direct thrombin inhibitor and low molecular weight heparin on platelet function in patients with coronary artery disease: A prospective interventional trialAdv. Ther.37(1),420-430(2020)
Ferroni, P., Riondino, S., Vazzana, N., et al.Biomarkers of platelet activation in acute coronary syndromesThromb. Haemost.108(6),1109-1123(2012)
Patrono, C., Ciabattoni, G., Patrignani, P., et al.Evidence for a renal origin of urinary thromboxane B2 in health and diseaseAdv. Prostaglandin Thromboxane Leukot. Res.11,493-498(1983)
Lawson, J.A., Patrono, C., Ciabattoni, G., et al.Long-lived enzymatic metabolites of thromboxane B2 in the human circulationAnal. Biochem.155(1),198-205(1986)