Leukotriene E4
Cat. No.:YN480589
产品名称: | Leukotriene E4 |
CAS No.: | 75715-89-8 |
Chemical Name: | 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
Synonyms: | LTE4 |
分子量: | 439.61 |
分子式: | C₂₃H₃₇NO₅S |
SMILES: | CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E |
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Bernström, K., and Hammarström, S.Metabolism of leukotriene D by porcine kidneyJ. Biol. Chem.256(18),9579-9582(1981)
Samuelsson, B.Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammationScience220(4597),568-575(1983)
Lefer, A.M.Leukotrienes as mediators of ischemia and shockBiochem. Pharmacol.35(2),123-127(1986)
Kumlin, M., Stensvad, F., Larsson, L., et al.Validation and application of a new simple strategy for measurements of urinary leukotriene E4 in humansClin. Exp. Allergy25(5),467-479(1995)
Drazen, J.M., O'Brien, J., Sparrow, D., et al.Recovery of leukotriene E4 from the urine of patients with airway obstructionAm. Rev. Respir. Dis.146(1),104-108(1992)
Kumlin, M., Dahlén, B., Björck, T., et al.Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmaticsAm. Rev. Respir. Dis.146(1),96-103(1992)