3β-Ursodeoxycholic acid
Cat. No.：YN480590
CAS No. ：78919-26-3
规格
价格(RMB)
库存
| 产品名称: | 3β-Ursodeoxycholic acid |
| CAS No.: | 78919-26-3 |
| Chemical Name: | (3β,5β,7β)-3,7-dihydroxy-cholan-24-oic acid |
| Synonyms: | 3β-熊去氧胆酸; Isoursodeoxycholic acid |
| 分子量: | 392.57 |
| 分子式: | C₂₄H₄₀O₄ |
| SMILES: | C[C@@]12-;@[C@](-;@C-;@C-;@[C@]-;@2([H])[C@H](C)CCC(O)=O)([H])-;@[C@@]3([H])-;@[C@](-;@[C@@]4(-;@[C@](-;@C-;@[C@@H](O)-;@C-;@C-;@4)([H])-;@C-;@[C@@H]-;@3O)C)([H])-;@C-;@C-;@1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) 是胆汁酸。 3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) 通过口服给药显示出良好的耐受性和良好的肠道吸收。3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) 可以被肠和肝酶异构化并产生 UDCA。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Marschall, H.-U., Broomé, U., Einarsson, C., et al.Isoursodeoxycholic acid: Metabolism and therapeutic effects in primary biliary cirrhosisJ. Lipid Res.42(5),735-742(2001)
Beuers, U., Fischer, S., Spengler, U., et al.Formation of iso-ursodeoxycholic acid during administration of ursodeoxycholic acid in manJ. Hepatol.13(1),97-103(1991)
Purucker, E., Marschall, H.-U., Winograd, R., et al.Metabolism and effects on cholestasis of isoursodeoxycholic and ursodeoxycholic acids in bile duct ligated ratsBiochim. Biophys. Acta1526(1),44-52(2001)
