Salcaprozate sodium
Cat. No.:YN480611
产品名称: | Salcaprozate sodium |
CAS No.: | 203787-91-1 |
Chemical Name: | 8-[(2-hydroxybenzoyl)amino]-octanoic acid, monosodium salt |
Synonyms: | SNAC |
分子量: | 301.31 |
分子式: | C₁₅H₂₀NNaO₄ |
SMILES: | O=C(O[Na])CCCCCCCNC(C1=CC=CC=C1O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Salcaprozate sodium (SNAC) 是一种口服吸收促进剂,有潜力作为口服形式的肝素和胰岛素的递送剂。Salcaprozate sodium 可增加非共价大分子络合引起的亲脂性,从而增加小肠上皮细胞的被动跨细胞渗透。 |
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Xu, Y., Amakye, W.K., Xiao, G., et al.Intestinal absorptivity-increasing effects of sodium N-[8-(2-hydroxybenzoyl)amino]-caprylate on food-derived bioactive peptideFood Chem.401,134059(2023)
Burshtein, G., Itin, C., Tang, J.C.Y., et al.The combined effect of permeation enhancement and proteolysis inhibition on the systemic exposure of orally administrated peptides: Salcaprozate sodium, soybean trypsin inhibitor, and teriparatide study in pigsInt. J. Pharm. X.3,100097(2021)