N,N'-Diacetyl-L-cystine
Cat. No.：YN480614
CAS No. ：5545-17-5
规格
价格(RMB)
库存
| 产品名称: | N,N'-Diacetyl-L-cystine |
| CAS No.: | 5545-17-5 |
| Chemical Name: | (2R,2'R)-3,3'-disulfanediylbis(2-acetamidopropanoic acid) |
| Synonyms: | DiNAC; (Ac-Cys-OH)2 |
| 分子量: | 324.37 |
| 分子式: | C₁₀H₁₆N₂O₆S₂ |
| SMILES: | O=C(O)[C@H](CSSC[C@@H](C(O)=O)NC(C)=O)NC(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | N,N'-diacetyl-L-cystine (DiNAC) 是一种具有免疫调节特性的 N-乙酰基半胱氨酸的二硫二聚体。N,N'-diacetyl-L-cystine 是啮齿类动物中接触敏感/迟发型超敏反应的有效口服活性调节剂。N,N'-diacetyl-L-cystine 在高脂血症兔 (WHHL) 中也具有抗动脉粥样硬化的作用。 |
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Särnstrand, B., Jansson, A.H., Matuseviciene, G., et al.N,N'-Diacetyl-L-cystine-the disulfide dimer of N-acetylcysteine-is a potent modulator of contact sensitivity/delayed type hypersensitivity reactions in rodentsJ. Pharmacol. Exp. Ther.288(3),1174-1184(1999)
Pettersson, K., and Bergstrand, H.The antiatherogenic effect of DiNAC: Experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseasesCardiovasc. Drug Rev.21(2),119-132(2003)
Wågberg, M., Jansson, A.H., Westerlund, C., et al.N,N'-Diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: Evidence for immunomodulatory agents as a new approach to prevent atherosclerosisJ. Pharmacol. Exp. Ther.299(1),76-82(2001)
Pettersson, K.S., Eliasson, U.B., Abrahamsson, T., et al.N,N-Diacetyl-L-cystine improves endothelial function in atherosclerotic watanabe heritable hyperlipidaemic rabbitsBasic Clin. Pharmacol. Toxicol.100(1),36-42(2007)
