CB-6644
Cat. No.：YN480620
CAS No. ：2316817-88-4
规格
价格(RMB)
库存
| 产品名称: | CB-6644 |
| CAS No.: | 2316817-88-4 |
| Chemical Name: | 5-chloro-N-[4-[[6,7-dihydro-3-(methoxymethyl)-1-oxo-1H,5H-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxobutyl]-2-ethoxy-4-fluoro-benzamide |
| Synonyms: | 5-Chloro-2-ethoxy-4-fluoro-N-[4-[[3-(methoxymethyl)-1-oxo-6,7-dihydro-5H-pyrazolo[1,2-a][1,2]benzodi;5-Chloro-2-ethoxy-4-fluoro-N-(4-((3-(methoxymethyl)-1-oxo-6,7-dihydro-1H,5H-benzo[c]pyrazolo[1,2-a][1,2]diazepin-2-yl)amino)-2,2-dimethyl-4-oxobutyl)benza |
| 分子量: | 573.06 |
| 分子式: | C₂₉H₃₄ClFN₄O₅ |
| SMILES: | COCC1=C(NC(CC(C)(C)CNC(C2=C(OCC)C=C(F)C(Cl)=C2)=O)=O)C(N(N1CCC3)C4=C3C=CC=C4)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CB-6644 一种选择性的RUVBL1/2复合体抑制剂。抑制 RUVBL1/2 的 ATP 酶活性，IC50为 15 nM。具有抗癌活性。 |
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Assimon, V.A., Tang, Y., Vargas, J.D., et al.CB-6644 is a selective inhibitor of the RUVBL1/2 complex with anticancer activityACS Chem Biol.14(2),236-244(2019)
