α-Truxillic acid
Cat. No.：YN480630
CAS No. ：490-20-0
规格
价格(RMB)
库存
| 产品名称: | α-Truxillic acid |
| CAS No.: | 490-20-0 |
| Chemical Name: | (1α,2α,3β,4β)-2,4-diphenyl-1,3-cyclobutanedicarboxylic acid |
| Synonyms: | |
| 分子量: | 296.32 |
| 分子式: | C₁₈H₁₆O₄ |
| SMILES: | OC([C@H]1[C@@H]([C@@H]([C@H]1C2=CC=CC=C2)C(O)=O)C3=CC=CC=C3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | α-Truxillic acid 是由两个 α-trans-cinnamic acid 分子构成的二聚体，具有抗炎活性。 |
| IC50和靶点: | |
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Benedict, J.B., and Coppens, P.Kinetics of the single-crystal to single-crystal two-photon photodimerization of α-trans-cinnamic acid to α-truxillic acidJ. Phys. Chem. A113(13),3116-3120(2009)
Chi, Y.M., Nakamura, M., Yoshizawa, T., et al.Anti-inflammatory activities of α-truxillic acid derivatives and their monomer componentsBiol. Pharm. Bull.28(9),1776-1778(2005)
Chi, Y.M., Nakamura, M., Zhao, X.Y., et al.Antinociceptive activities of α-truxillic acid and β-truxillic acid derivativesBiol. Pharm. Bull.29(3),580-584(2006)
Berger, W.T., Ralph, B.P., Kaczocha, M., et al.Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugsPLoS One7(12),(2012)
Kaczocha, M., Glaser, S.T., and Deutsch, D.G.Identification of intracellular carriers for the endocannabinoid anandamideProc. Natl. Acad. Sci. USA106(15),6375-6380(2009)
Steri, R., Rupp, M., Proschak, E., et al.Truxillic acid derivatives act as peroxisome proliferator-activated receptor γ activatorsBioorg. Med. Chem. Lett.20(9),2920-2923(2010)
