ML-180
Cat. No.：YN480644
CAS No. ：863588-32-3
规格
价格(RMB)
库存
| 产品名称: | ML-180 |
| CAS No.: | 863588-32-3 |
| Chemical Name: | 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione |
| Synonyms: | SR1848 |
| 分子量: | 388.89 |
| 分子式: | C₂₀H₂₅ClN₄O₂ |
| SMILES: | O=C1N(C2CCCCC2)C(C=C(N3CCN(C4=CC=CC(Cl)=C4)CC3)N1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML-180 (SR1848) 是一种有效的孤儿核受体肝受体同源物 1 (LRH-1;NR5A2) 反向激动剂，IC50为 3.7 µM。ML-180 不抑制类固醇生成因子 1 (SF-1;NR5A1; IC50>10 µM)。 ML-180 具有抗依赖 LRH-1 癌症的潜力。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Busby, S., Nuhant, P., Cameron, M., et al.Discovery of inverse agonists for the liver receptor homologue-1 (LRH1; NR5A2),1-55(2010)
