BIBB 515
Cat. No.：YN480651
CAS No. ：156635-05-1
规格
价格(RMB)
库存
| 产品名称: | BIBB 515 |
| CAS No.: | 156635-05-1 |
| Chemical Name: | 1-(4-chlorobenzoyl)-4-[[4-(4,5-dihydro-2-oxazolyl)phenyl]methylene]-piperidine |
| Synonyms: | |
| 分子量: | 380.87 |
| 分子式: | C₂₂H₂₁ClN₂O₂ |
| SMILES: | O=C(C1=CC=C(C=C1)Cl)N2CC/C(CC2)=C\C3=CC=C(C=C3)C4=NCCO4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BIBB 515 是一种有效的，选择性的和口服活性的 2,3-氧化角鲨烯环化酶 (OSC) 抑制剂，在大鼠和小鼠中的ED50值分别为 0.2-0.5 mg/kg 和 0.36-33.3 mg/kg (1-5 小时)。BIBB 515 主要通过抑制低密度脂蛋白 (LDL) 的产生来发挥降脂作用。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Eisele, B., Budzinski, R., Müller, P., et al.Effects of a novel 2,3-oxidosqualene cyclase inhibitor on cholesterol biosynthesis and lipid metabolism in vivoJ. Lipid Res.38,564-574(1997)
