Lipofermata
Cat. No.:YN480659
产品名称: | Lipofermata |
CAS No.: | 297180-15-5 |
Chemical Name: | 5-bromo-5'-phenyl-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one |
Synonyms: | 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiaz ole]-2-one;Lipofermata |
分子量: | 360.23 |
分子式: | C₁₅H₁₀BrN₃OS |
SMILES: | O=C1NC2=C(C=C(Br)C=C2)C13SC(C4=CC=CC=C4)=NN3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Lipofermata 是一种脂肪酸转运蛋白(FATP)抑制剂,能消除脂质转运进入黑色素瘤细胞,减少黑色素瘤的生长和侵袭。 |
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Sandoval, A., Chokshi, A., Jesch, E.D., et al.Identification and characterization of small compound inhibitors of human FATP2Biochem. Pharmacol.79(7),990-999(2010)
Ahowesso, C., Black, P.N., Saini, N., et al.Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell deathBiochem. Pharmacol.98(1),167-181(2015)