Ibrolipim
Cat. No.：YN480675
CAS No. ：133208-93-2
规格
价格(RMB)
库存
| 产品名称: | Ibrolipim |
| CAS No.: | 133208-93-2 |
| Chemical Name: | [[4-[[(4-bromo-2-cyanophenyl)amino]carbonyl]phenyl]methyl]-phosphonic acid diethyl ester |
| Synonyms: | NO-1886 |
| 分子量: | 451.25 |
| 分子式: | C₁₉H₂₀BrN₂O₄P |
| SMILES: | BrC1=CC(C#N)=C(C=C1)NC(C2=CC=C(C=C2)CP(OCC)(OCC)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ibrolipim (NO-1886) 是一种口服活性的脂蛋白脂肪酶 (LPL) 激活剂。 Ibrolipim 可降低血浆甘油三酸酯，增加高密度脂蛋白胆固醇水平。 Ibrolipim 具有肾保护和降血脂的作用。 |
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Yin, W., and Tsutsumi, K.Lipoprotein lipase activator NO-1886Cardiovasc. Drug Rev.21(2),133-142(2003)
Tsutsumi, K., Inoue, Y., Shima, A., et al.The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosisJ. Clin. Invest.92(1),411-417(1993)
