ESI-05
Cat. No.：YN480678
CAS No. ：5184-64-5
规格
价格(RMB)
库存
| 产品名称: | ESI-05 |
| CAS No.: | 5184-64-5 |
| Chemical Name: | 1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]-benzene |
| Synonyms: | NSC 116966 |
| 分子量: | 274.38 |
| 分子式: | C₁₆H₁₈O₂S |
| SMILES: | O=S(C1=C(C)C=C(C)C=C1C)(C2=CC=C(C)C=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ESI-05 (NSC 116966) 是一种特异性的 cAMP 直接激活交换蛋白 2 (EPAC2) 拮抗剂，IC50值为 0.4 µM，抑制 cAMP 诱导的 EPAC2 的活化，和 EAPC2 介导的 Rap1 的活化。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Tsalkova, T., Mei, F.C., Li, S., et al.Isoform-specific antagonists of exchange proteins directly activated by cAMPProc. Natl. Acad. Sci. USA109(45),18613-18618(2012)
