GSK2194069
Cat. No.：YN480774
CAS No. ：1332331-08-4
规格
价格(RMB)
库存
| 产品名称: | GSK2194069 |
| CAS No.: | 1332331-08-4 |
| Chemical Name: | 4-[4-(5-benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one |
| Synonyms: | GSK 2194069;GSK-2194069 |
| 分子量: | 428.48 |
| 分子式: | C₂₅H₂₄N₄O₃ |
| SMILES: | O=C(N1C[C@H](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK2194069是有效和特异的β-酮酰还原酶（KR）抑制剂，在检测释放CoA 实验中的IC50分别为7.7±4.1nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Hardwicke, M.A., Rendina, A.R., Williams, S.P., et al.The uptake and subcellular distribution of radio-labeled metabolites of digoxin in the isolated perfused guinea-pig heartNaunyn Schmiedebergs Arch. Pharmacol.292(3),251-254(1976)
