CD38 inhibitor 1
Cat. No.:YN480795
产品名称: | CD38 inhibitor 1 |
CAS No.: | 1700637-55-3 |
Chemical Name: | 4-[[trans-4-(2-methoxyethoxy)cyclohexyl]amino]-1-methyl-6-(5-thiazolyl)-2(1H)-quinolinone |
Synonyms: | CD38-IN-78c, MDK-7553 |
分子量: | 413.53 |
分子式: | C₂₂H₂₇N₃O₃S |
SMILES: | O=C1N(C)C2=C(C=C(C3=CN=CS3)C=C2)C(N[C@H]4CC[C@H](OCCOC)CC4)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CD38 inhibitor 1 (compound 78c) 是一种有效的CD38抑制剂,在人类和小鼠中的 CD38 的IC50分别为 7.3 nM 和 1.9 nM。 |
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Tarragó, M.G., Chini, C.C.S., Kanamori, K.S., et al.A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ declineCell Metab.27(5),1081-1095e1010(2018)