WS3
Cat. No.:YN480808
产品名称: | WS3 |
CAS No.: | 1421227-52-2 |
Chemical Name: | N-[6-[4-[[[[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-4-pyrimidinyl]-cyclopropanecarboxamide |
Synonyms: | WS-3; WS 3 |
分子量: | 569.58 |
分子式: | C₂₈H₃₀F₃N₇O₃ |
SMILES: | O=C(C1CC1)NC2=NC=NC(OC3=CC=C(NC(NC4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4)=O)C=C3)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | WS3 是一种的增殖分子,可促进鼠和人原代胰岛的胰腺 β 细胞增殖 (β cell proliferation)。WS3 可用于 I 型糖尿病的研究。 |
IC50和靶点: | |
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Shen, W., Tremblay, M.S., Deshmukh, V.A., et al.Small-molecule inducer of β cell proliferation identified by highthroughput screeningJ. Am. Chem. Soc.135(5),1669-1672(2013)
Swoboda, J.G., Elliott, J., Deshmukh, V., et al.Small molecule mediated proliferation of primary retinal pigment epithelial cellsACS Chem. Biol.8(7),1407-1411(2013)