PZ-2891
Cat. No.:YN480810
产品名称: | PZ-2891 |
CAS No.: | 2170608-82-7 |
Chemical Name: | |
Synonyms: | PZ2891 |
分子量: | 349.43 |
分子式: | C₂₀H₂₃N₅O |
SMILES: | N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PZ-2891 是一种可口服,能渗透血脑屏障的泛酸激酶 (PANK)调节剂。PZ-2891 在高浓度下充当正构抑制剂,在较低亚饱和浓度下充当变构激活剂。PZ-2891 抑制人泛酸激酶 PANK1β,PANK2 和 PANK3,IC50分别为 40.2 nM,0.7 nM 和 1.3 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |