Secologanin
Cat. No.：YN480831
CAS No. ：19351-63-4
规格
价格(RMB)
库存
| 产品名称: | Secologanin |
| CAS No.: | 19351-63-4 |
| Chemical Name: | (2S,3R,4S)-3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-(2-oxoethyl)-2H-pyran-5-carboxylic acid, methyl ester |
| Synonyms: | |
| 分子量: | 388.37 |
| 分子式: | C₁₇H₂₄O₁₀ |
| SMILES: | OC[C@H]1O[C@H]([C@@H]([C@H]([C@@H]1O)O)O)O[C@]2([C@@H]([C@@H](C(C(OC)=O)=CO2)CC=O)C=C)[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Secologanin 是一种裂环烯醚萜苷类化合物，是生物活性单萜类吲哚类生物碱 (如利血平 (HY-N0480)、Ajmaline 和长春碱) 生物合成的关键萜类中间体。Secologanin 合成酶 (细胞色素 P450 亚型 CYP72A1) 催化 loganin 氧化裂解为 Secologanin。 |
| IC50和靶点: | |
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Battersby, A.R., Burnett, A.R., and Parsons, P.G.Alkaloid biosynthesis. XIV. Secologanin: Its conversion into ipecoside and its role as biological precursor of the indole alkaloidsJ. Chem. Soc. C Organic8,1187-1192(1969)
Miettinen, K., Dong, L., Navrot, N., et al.The seco-iridoid pathway from Catharanthus roseusNat. Commun.5:3606,(2014)
Irmler, S., Schröder, G., St-Pierre, B., et al.Indole alkaloid biosynthesis in Catharanthus roseus: New enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthasePlant J.24(6),797-804(2000)
