5(S)-HPETE
Cat. No.:YN480838
产品名称: | 5(S)-HPETE |
CAS No.: | 71774-08-8 |
Chemical Name: | 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
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分子量: | 336.47 |
分子式: | C₂₀H₃₂O₄ |
SMILES: | CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)CCCC(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs. |
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Shimizu, T., Rådmark, O., and Samuelsson, B.Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acidProc. Natl. Acad. Sci. USA81,689-693(1984)
Haliday, E.M., Ramesha, C.S., and Ringold, G.TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metaboliteEMBO J.10,109-115(1991)