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5(S)​-​HPETE

Cat. No.:YN480838

  • CAS No. :71774-08-8

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    • 产品名称: 5(S)​-​HPETE
      CAS No.: 71774-08-8
      Chemical Name: 5S-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
      Synonyms:
      分子量:336.47
      分子式:C₂₀H₃₂O₄
      SMILES:CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)CCCC(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.
      IC50和靶点:
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    • Shimizu, T., Rådmark, O., and Samuelsson, B.Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acidProc. Natl. Acad. Sci. USA81,689-693(1984)

      Haliday, E.M., Ramesha, C.S., and Ringold, G.TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metaboliteEMBO J.10,109-115(1991)

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