FB23-2
Cat. No.：YN480887
CAS No. ：2243736-45-8
规格
价格(RMB)
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| 产品名称: | FB23-2 |
| CAS No.: | 2243736-45-8 |
| Chemical Name: | 2-[[2,6-dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]-N-hydroxy-benzamide |
| Synonyms: | |
| 分子量: | 392.24 |
| 分子式: | C₁₈H₁₅Cl₂N₃O₃ |
| SMILES: | O=C(NO)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)ON=C3C)C=C2Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | FB23-2 是一种有效、选择性的 mRNA N6- 甲基腺嘌呤脱甲基酶FTO抑制剂，IC50值为 2.6 μM。FB23-2 具有抗增殖作用。FB23-2 能用于急性髓系白血病 (AML) 的研究。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Huang, Y., Su, R., Sheng, Y., et al.Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemiaCancer Cell35(4),677-691.e610(2019)
