SKF-34288 hydrochloride
Cat. No.：YN480960
CAS No. ：320386-54-7
规格
价格(RMB)
库存
| 产品名称: | SKF-34288 hydrochloride |
| CAS No.: | 320386-54-7 |
| Chemical Name: | 3-mercapto-2-pyridinecarboxylic acid, monohydrochloride |
| Synonyms: | 3-Mercaptopicolinic acid hydrochloride |
| 分子量: | 191.64 |
| 分子式: | C₆H₆ClNO₂S |
| SMILES: | O=C(C1=NC=CC=C1S)O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SKF-34288 hydrochloride 是磷酸烯醇丙酮酸羧激酶 (PEPCK) 抑制剂。SKF-34288 hydrochloride 通过糖异生途径中 PEPCK 的特异性抑制来抑制葡萄糖合成，是一种有效的降血糖药。SKF-34288 hydrochloride 抑制 Asn 代谢并导致氨基酸和酰胺的增加。 |
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DiTullio, N.W., Berkoff, C.E., Blank, B., et al.3-mercaptopicolinic acid, an inhibitor of gluconeogenesisBiochem. J.138(3),387-394(1974)
Robinson, B.H., and Oei, J.3-Mercaptopicolinic acid, a preferential inhibitor of the cytosolic phosphoenolpyruvate carboxykinaseFEBS Lett.58(1),12-15(1975)
Hidalgo, J., Latorre, P., Carrodeguas, J.A., et al.Inhibition of pig phosphoenolpyruvate carboxykinase isoenzymes by 3-mercaptopicolinic acid and novel inhibitorsPLoS One11(7),e0159002(2016)
