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Benzyl-α-GalNAc

Cat. No.:YN480978

  • CAS No. :3554-93-6

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    • 产品名称: Benzyl-α-GalNAc
      CAS No.: 3554-93-6
      Chemical Name: phenylmethyl 2-(acetylamino)-2-deoxy-α-D-galactopyranoside
      Synonyms:O-glycosylation-IN-1
      分子量:311.33
      分子式:C₁₅H₂₁NO₆
      SMILES:O[C@@H]([C@H]([C@@H](CO)O1)O)[C@@H](NC(C)=O)[C@H]1OCC2=CC=CC=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Benzyl-α-GalNAc 是一种有效的 O-糖基化 (O-glycosylation) 抑制剂,用于减少细胞表面的粘蛋白。Benzyl-α-GalNAc 抑制人胰腺癌细胞模型黏蛋白 O-糖基化的合成。
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    • Niv, Y., Byrd, J.C., Ho, S.B., et al.Mucin synthesis and secretion in relation to spontaneous differentiation of colon cancer cells in vitroInt. J. Cancer50(1),147-152(1992)

      Kalra, A.V., and Campbell, R.B.Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: Overcoming cellular barriers for therapeutic gainBr. J. Cancer97(7),910-918(2007)

      Bresalier, R.S., Niv, Y., Byrd, J.C., et al.Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasisJ. Clin. Invest.87(3),1037-1045(1991)

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