Bretylium tosylate
Cat. No.：YN480983
CAS No. ：61-75-6
规格
价格(RMB)
库存
| 产品名称: | Bretylium tosylate |
| CAS No.: | 61-75-6 |
| Chemical Name: | 2-bromo-N-ethyl-N,N-dimethyl-benzenemethanaminium, 4-methylbenzenesulfonate (1:1) |
| Synonyms: | 托西溴苄铵 |
| 分子量: | 414.36 |
| 分子式: | C₁₈H₂₄BrNO₃S |
| SMILES: | C[N+](C)(CC)CC1=CC=CC=C1Br.O=S(C2=CC=C(C)C=C2)([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bretylium (tosylate)是血管收缩的神经递质突触前释放的抑制剂，是交感神经和肾上腺素神经的阻断剂。 |
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Helms, J.B., Arnett, K.L., Gatto, C., et al.Bretylium, an organic quaternary amine, inhibits the Na,K-ATPase by binding to the extracellular K-siteBlood Cells Mol. Dis.32(3),394-400(2004)
Boura, A.L., Copp, F.C., and Green, A.F.New antiadrenergic compoundsNature184,BA70-BA71(1959)
Brain, K.L., and Cunnane, T.C.Bretylium abolishes neurotransmitter release without necessarily abolishing the nerve terminal action potential in sympathetic terminalsBr. J. Pharmacol.153(4),831-839(2007)
Holland, K., Patterson, E., and Lucchesi, B.R.Prevention of ventricular fibrillation by bretylium in a conscious canine model of sudden coronary deathAm. Heart J.105(5),711-717(1983)
