DS18561882
Cat. No.:YN481001
产品名称: | DS18561882 |
CAS No.: | 2227149-22-4 |
Chemical Name: | |
Synonyms: | DS18561882;(S)-N-(4-(8-(3,4-Dimethylpiperazin-1-yl)-7-methyl-5-oxo-1,3,4,5-tetrahydro-2H-chromeno[3,4-c]pyridine-3-carbonyl)-2-(trifluoromethoxy)phenyl)methanesulfonamide;N-[4-[8-[(3S)-3,4-Dimethylpiperazin-1-yl]-7-methyl-5-oxo-2,4-dihydro-1H-chromeno[3,4 |
分子量: | 608.63 |
分子式: | C₂₈H₃₁F₃N₄O₆S |
SMILES: | CS(=O)(NC1=CC=C(C(N2CCC(C3=CC=C(N4C[C@H](C)N(C)CC4)C(C)=C3O5)=C(C5=O)C2)=O)C=C1OC(F)(F)F)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | DS18561882 是一种高效的,对酶具有高选择性的亚甲基四氢叶酸脱氢酶 2 (MTHFD2) 抑制剂,IC50值为 0.0063 μM。DS18561882 抑制 MTHFD1 的IC50值是 0.57 μM。DS18561882 具有良好的口服药代动力学特性。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |