Oxothiazolidinecarboxylic acid
Cat. No.：YN481092
CAS No. ：19771-63-2
规格
价格(RMB)
库存
| 产品名称: | Oxothiazolidinecarboxylic acid |
| CAS No.: | 19771-63-2 |
| Chemical Name: | 2-oxo-(4R)-4-thiazolidinecarboxylic acid |
| Synonyms: | 丙半胱氨酸,Procysteine,Oxothiazolidine carboxylate |
| 分子量: | 147.15 |
| 分子式: | C₄H₅NO₃S |
| SMILES: | O=C([C@H]1NC(SC1)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oxothiazolidinecarboxylic acid 是一种抗氧化剂，是半胱氨酸的前药，它是惰性的，在细胞内代谢成半胱氨酸，从而刺激谷胱甘肽的合成。 |
| IC50和靶点: | |
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Williamson, J.M., and Meister, A.Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate, a 5-oxo-L-prolinase substrateProc. Natl. Acad. Sci. USA78(2),936-939(1981)
Lee, K.S., Park, H.S., Park, S.J., et al.A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthmaMol. Pharmacol.68(5),1281-1290(2005)
Promsote, W., Veeranan-Karmegam, R., Ananth, S., et al.L-2-oxothiazolidine-4-carboxylic acid attenuates oxidative stress and inflammation in retinal pigment epitheliumMol. Vis.20,73-88(2014)
