4-Hydroxyatomoxetine
Cat. No.：YN481093
CAS No. ：435293-66-6
规格
价格(RMB)
库存
| 产品名称: | 4-Hydroxyatomoxetine |
| CAS No.: | 435293-66-6 |
| Chemical Name: | 3-methyl-4-[(1R)-3-(methylamino)-1-phenylpropoxy]-phenol |
| Synonyms: | |
| 分子量: | 271.35 |
| 分子式: | C₁₇H₂₁NO₂ |
| SMILES: | OC1=CC=C(O[C@@H](C2=CC=CC=C2)CCNC)C(C)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4-Hydroxyatomoxetine 是Atomoxetine 的活性代谢产物。4-Hydroxyatomoxetine 通过细胞色素 P450 2D6 (CYP2D6) 酶代谢。Atomoxetine 是去甲肾上腺素重吸收抑制剂，与人 NET，SERT 和 DAT 的放射性配体结合的Ki分别为 5 nM，77 nM 和 1451 nM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Sauer, J.-M., Ring, B.J., and Witcher, J.W.Clinical pharmacokinetics of atomoxetineClin. Pharmacokinet.44(6),571-590(2005)
