N-Hexanoyl-L-homoserine lactone
Cat. No.:YN481168
产品名称: | N-Hexanoyl-L-homoserine lactone |
CAS No.: | 147852-83-3 |
Chemical Name: | N-[(3S)-tetrahydro-2-oxo-3-furanyl]-hexanamide |
Synonyms: | 己酰-L-高丝氨酸内酯,C6-HSL |
分子量: | 199.25 |
分子式: | C₁₀H₁₇NO₃ |
SMILES: | CCCCCC(N[C@@H]1C(OCC1)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | N- N-hexanoyl-L-Homoserine lactone regulates virulence in general and in cystic fibrosis, prevents infection, reduces slime and biofilm in commercial agriculture and aquaculture industries, prevents food spoilage, and septicemia in fish. |
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Gould, T.A., Herman, J., Krank, J., et al.Specificity of acyl-homoserine lactone syntheses examined by mass spectrometryJ. Bacteriol.188(2),773-783(2006)
Morohoshi, T., Inaba, T., Kato, N., et al.Identification of quorum-sensing signal molecules and the LuxRI homologs in fish pathogen edwardsiella tardaJ. Biosci. Bioeng.98(4),274-281(2004)
Ulrich, R.L., Hines, H.B., Parthasarathy, N., et al.Mutational analysis and biochemical characterization of the bukholderia thailandensis DW503 quorum-sensing networkJ. Bacteriol.186(13),4350-4360(2004)
Wang, L.H., Weng, L.X., Dong, Y.H., et al.Specificity and enzyme kinetics of the quorum-quenching N-acyl homoserine lactone lactonase (AHL-lactonase)J. Biol. Chem.279(14),13645-13651(2004)
Yates, E.A., Philipp, B., Buckley, C., et al.N-acylhomoserine lactones undergo lactonolysis in a pH-temperature-, and acyl chain length-dependent manner during growth of yersinia pseudotuberculosis and pseudomonas aeruginosaInfect. Immun.70(10),5635-5646(2002)
Luo, Z.Q., Su, S., and Farrand, S.K.In situ activation of the quorum-sensing transcription factor TraR by cognate and noncognate acyl-homoserine lactone ligands: Kinetics and consequencesJ. Bacteriol.186(19),5665-5672(2003)
Christensen, A.B., Riedel, K., Eberl, L., et al.Quorum-sensing-directed protein expression in Serratia proteamaculans B5aMicrobiology149(Pt 2),471-483(2003)
Chambers, C.E., Visser, M.B., Schwab, U., et al.Identification of N-acylhomoserine lactones in mucopurulent respiratory secretions from cystic fibrosis patientsFEMS Microbiol. Lett.244(2),297-304(2005)