ML281
Cat. No.:YN481183
产品名称: | ML281 |
CAS No.: | 1404437-62-2 |
Chemical Name: | N-[2-(3,4-dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide |
Synonyms: | ML 281,ML-281 |
分子量: | 389.47 |
分子式: | C₂₂H₁₉N₃O₂S |
SMILES: | O=C1NC2=CC=CC=C2N=C1C3=CC(C(C)C)=CC=C3NC(C4=CC=CS4)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ML281是一个强的,有选择性的STK33抑制剂,IC50值是14 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Weïwer, M., Spoonamore, J., Wei, J., et al.A potent and selective quinoxalinone-based STK33 inhibitor does not show synthetic lethality in KRAS-dependent cellsACS Med. Chem. Lett.3(12),1034-1038(2012)