ADH-1
Cat. No.:YN481221
产品名称: | ADH-1 |
CAS No.: | 229971-81-7 |
Chemical Name: | N-acetyl-L-cysteinyl-L-histidyl-L-alanyl-L-valyl-L-cysteinamide, cyclic (1→5)-disulfide |
Synonyms: | Exherin |
分子量: | 570.69 |
分子式: | C₂₂H₃₄N₈O₆S₂ |
SMILES: | O=C([C@@H](NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CC1=CN=CN1)N2)=O)=O)=O)CSSC[C@H](NC(C)=O)C2=O)N |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ADH-1 是一种N-cadherin的拮抗剂,能够抑制 N-cadherin 介导的细胞黏附。 |
IC50和靶点: | |
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Williams, E., Williams, G., Gour, B.J., et al.A novel family of cyclic peptide antagonists suggests that N-cadherin specificity is determined by amino acids that flank the HAV motifJ. Biol. Chem.275(6),4007-4012(2000)
Shintani, Y., Fukumoto, Y., Chaika, N., et al.ADH-1 suppresses N-cadherin-dependent pancreatic cancer progressionInt. J. Cancer122(1),71-77(2008)