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Malonyl Coenzyme A lithium

Cat. No.:YN481306

  • CAS No. :108347-84-8

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    • 产品名称: Malonyl Coenzyme A lithium
      CAS No.: 108347-84-8
      Chemical Name: S-(hydrogen propanedioate) coenzyme A, lithium salt
      Synonyms:
      分子量:暂无
      分子式:C₂₄H₃₈N₇O₁₉P₃S.xLi
      SMILES:O[C@H]([C@@H]1O[P](O)(O)=O)[C@](O[C@@H]1CO[P](O[P](OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(O)=O)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[x].[LiH]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Malonyl Coenzyme A (lithium) is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl Coenzyme A (lithium) is formed by the Acetyl CoA Carboxylase
      IC50和靶点:
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    • Hiltunen, J.K., Autio, K.J., Schonauer, M.S., et al.Mitochondrial fatty acid synthesis and respirationBiochim. Biophys. Acta1797(6-7),1195-1202(2010)

      Summers, R.G., Ali, A., Shen, B., et al.Malonyl-coenzyme A:Acyl carrier protein acyltransferase of Streptomyces glaucescens: A possible link between fatty acid and polyketide biosynthesisBiochem.34(29),9389-9402(1995)

      Pizer, E.S., Thupari, J., Han, W.F., et al.Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenograftsCancer Res.60,213-218(2000)

      Zhan, J.Biosynthesis of bacterial aromatic polyketidesCurr. Top. Med. Chem.9(17),1598-1610(2009)

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