Tin(IV) mesoporphyrin IX dichloride
Cat. No.：YN481344
CAS No. ：106344-20-1
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| 产品名称: | Tin(IV) mesoporphyrin IX dichloride |
| CAS No.: | 106344-20-1 |
| Chemical Name: | (OC-6-13)-dichloro[7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-stannate(2-), dihydrogen |
| Synonyms: | Stannsoporfin |
| 分子量: | 754.29 |
| 分子式: | C₃₄H₃₆Cl₂N₄O₄Sn |
| SMILES: | [Cl-][Sn+4]123([N-]4C5=C(CCC(O)=O)C(C)=C4C=C(C(CC)=C6C)[N]1=C6C=C(C(CC)=C7C)[N-]2C7=CC8=[N]3C(C(CCC(O)=O)=C8C)=C5)[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tin(IV) mesoporphyrin IX dichloride (Stannsoporfin) 是一种血红素加氧酶(HO)抑制剂，被开发用于预防婴儿高胆红素血症发展为黄疸, 详细信息请参考专利文献 WO2011103196A1。 |
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Drummond, G.S., and Kappas, A.Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidationProc. Natl. Acad. Sci. USA78(10),6466-6470(1981)
Hamori, C.J., Vreman, H.J., and Stevenson, D.K.Suppression of carbon monoxide excretion by zinc mesoporphyrin in adult Wistar rats: Evidence for potent in vivo inhibition of bilirubin productionRes. Commun. Chem. Pathol. Pharmacol.62(1),41-48(1988)
Chen, T.m., Li, J., Fan, L., et al.Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal model of hypertensive myocardial infarctionInt. J. Mol. Sci.14(2),2684-2706(2013)
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Zhang, L., Gan, Z.K., Han, L.N., et al.Protective effect of heme oxygenase-1 on Wistar rats with heart failure through the inhibition of inflammation and amelioration of intestinal microcirculationJ.Geriatr.Cardiol.12(4),353-365(2015)
