Sardomozide dihydrochloride
Cat. No.：YN481359
CAS No. ：138794-73-7
规格
价格(RMB)
库存
| 产品名称: | Sardomozide dihydrochloride |
| CAS No.: | 138794-73-7 |
| Chemical Name: | 2-[4-(aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene]-hydrazinecarboximidamide, dihydrochloride |
| Synonyms: | CGP 48664A |
| 分子量: | 303.19 |
| 分子式: | C₁₁H₁₆Cl₂N₆ |
| SMILES: | N=C(C1=CC=CC2=C1CC/C2=N\NC(N)=N)N.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sardomozide dihydrochloride 是一种 S-腺苷甲硫氨酸脱羧酶 (SAMDC) 抑制剂，其IC50值为 5 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Stanek, J., Caravatti, G., Frei, J., et al.4-Amidinoindan-1-one 2'-amidinohydrazone: A new potent and selective inhibitor of S-Adenosylmethionine decarboxylaseJ. Med. Chem.36(15),2168-2171(1993)
Regenass, U., Mett, H., Stanek, J., et al.CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activityCancer Res.54(12),3210-3217(1994)
Schäfer, B., Hauber, I., Bunk, A., et al.Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activityJ. Infect. Dis.194(6),740-750(2006)
