Methyl pyropheophorbide-a
Cat. No.：YN481360
CAS No. ：6453-67-4
规格
价格(RMB)
库存
| 产品名称: | Methyl pyropheophorbide-a |
| CAS No.: | 6453-67-4 |
| Chemical Name: | 9-ethenyl-14-ethyl-4S,8,13,18-tetramethyl-20-oxo-3S-phorbinepropanoic acid, methyl ester |
| Synonyms: | Pyropheophorbide-a methyl ester |
| 分子量: | 548.67 |
| 分子式: | C₃₄H₃₆N₄O₃ |
| SMILES: | CC1=C(N2)/C=C(C(CC)=C3C)\N=C3/C=C(C(C=C)=C/4C)\NC4=C/C5=N/C([C@H]([C@@H]5C)CCC(OC)=O)=C(C6)\C2=C1C6=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester)，叶绿素 a 的衍生物，是一种有效的光敏剂，可用于癌症的光动力疗法 (PDT)。Methyl pyropheophorbide-a 具有光动力学活性，可以诱导细胞凋亡并抑制肿瘤的生长。 |
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Chen, Y., Zheng, X., Dobhal, M.P., et al.Methyl pyropheophorbide-a analogues: Potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacyJ. Med. Chem.48(11),3692-3695(2005)
Matroule, J.-Y., Bonizzi, G., Morlière, P., et al.Pyropheophorbide-a methyl ester-mediated photosensitization activates transcription factor NF-κB through the interleukin-1 receptor-dependent signaling pathwayJ. Biol. Chem.274(5),2988-3000(1999)
