Trilostane
Cat. No.：YN481387
CAS No. ：13647-35-3
规格
价格(RMB)
库存
| 产品名称: | Trilostane |
| CAS No.: | 13647-35-3 |
| Chemical Name: | 4α,5α-epoxy-3,17β-dihydroxy-androst-2-ene-2-carbonitrile |
| Synonyms: | 曲洛司坦; Win 24540 |
| 分子量: | 329.43 |
| 分子式: | C₂₀H₂₇NO₃ |
| SMILES: | OC1=C(C#N)C[C@@]2(C)[C@@]3(CC[C@]4([H])[C@]2([H])CC[C@@]5(C)[C@@]4([H])CC[C@@H]5O)[C@@H]1O3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trilostane(Win 24540; Modrastane)是3 β-羟化类固醇脱氢酶抑制剂，可作用于库兴氏综合征。 |
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Thomas, J.L., Mack, V.L., Glow, J.A., et al.Structure/function of the inhibition of human 3β-hydroxysteroid dehydrogenase type 1 and type 2 by trilostaneJ. Steroid Biochem. Mol. Biol.111(1-2),66-73(2008)
Machida, T., Uchida, E., Matsuda, K., et al.Aldosterone-, corticosterone- and cortisol-secreting adrenocortical carcinoma in a dog: Case reportJ. Vet. Med. Sci.70(3),317-320(2008)
Thomas, J.L., Bucholtz, K.M., and Kacsoh, B.Selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 as a potential treatment for breast cancerJ. Steroid Biochem. Mol. Biol.125(1-2),57-65(2011)
