Cetilistat
Cat. No.：YN481392
CAS No. ：282526-98-1
规格
价格(RMB)
库存
| 产品名称: | Cetilistat |
| CAS No.: | 282526-98-1 |
| Chemical Name: | 2-(hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one |
| Synonyms: | 新利司他; ATL-962 |
| 分子量: | 401.58 |
| 分子式: | C₂₅H₃₉NO₃ |
| SMILES: | CC1=CC=C(N=C(OCCCCCCCCCCCCCCCC)OC2=O)C2=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cetilistat (ATL-962) 是一种胰腺脂肪酶 (pancreatic lipase) 抑制剂，可作为有效的抗肥胖药。Cetilistat 抑制大鼠和人胰脂肪酶活性，IC50分别为 54.8 nM 和 5.95 nM。 |
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Yamada, Y., Kato, T., Ogino, H., et al.Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in ratsHorm. Metab. Res.40(8),539-543(2008)
Yuan, S., Chan, J.F.W., Chik, K.K.H., et al.Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening systemPharmacol. Res.159,104960(2020)
