Lomitapide
Cat. No.：YN481400
CAS No. ：182431-12-5
规格
价格(RMB)
库存
| 产品名称: | Lomitapide |
| CAS No.: | 182431-12-5 |
| Chemical Name: | N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide |
| Synonyms: | 洛美他派; AEGR-733; BMS-201038 |
| 分子量: | 693.72 |
| 分子式: | C₃₉H₃₇F₆N₃O₂ |
| SMILES: | O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lomitapide (AEGR-733; BMS-201038)是高效的微粒体甘油三酯转移蛋白(MTP)抑制剂， 体内试验的IC50值为8 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Wetterau, J.R., Gregg, R.E., Harrity, T.W., et al.An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbitsScience282(5389),751-754(1998)
