Tafamidis meglumine
Cat. No.：YN481404
CAS No. ：951395-08-7
规格
价格(RMB)
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| 产品名称: | Tafamidis meglumine |
| CAS No.: | 951395-08-7 |
| Chemical Name: | Vyndaqel |
| Synonyms: | 他发米帝司甲葡胺; Fx-1006A |
| 分子量: | 503.33 |
| 分子式: | C₂₁H₂₄Cl₂N₂O₈ |
| SMILES: | O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O.O[C@@H]([C@@H]([C@@H](CO)O)O)[C@@H](O)CNC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tafamidis meglumine (Fx-1006A) 是一种有效、选择性的transthyretin (TTR)稳定剂，对野生型 WT-TTR 和突变型同源四聚体 V30M-TTR，V122I-TTR 的活性相当，EC50值为 2.7-3.2 μM。Tafamidis meglumine 抑制淀粉样蛋白的生成。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Ivanov, J., et al.: ACS Omega. 5, 42 (2020)
