Repaglinide D5
Cat. No.:YN481425
产品名称: | Repaglinide D5 |
CAS No.: | 1217709-85-7 |
Chemical Name: | 2-(ethoxy-1,1,2,2,2-d5)-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]-benzoic acid |
Synonyms: | 瑞格列奈 D5; AG-EE 623ZW D5 |
分子量: | 457.62 |
分子式: | C₂₇H₃₁D₅N₂O₄ |
SMILES: | O=C(O)C1=CC=C(CC(N[C@H](C2=CC=CC=C2N3CCCCC3)CC(C)C)=O)C=C1OC([2H])([2H])C([2H])([2H])[2H] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Repaglinide D5 (AG-EE 623ZW D5) 是 Repaglinide 的氘代物。Repaglinide 是用作 2 型糖尿病的胰岛素促分泌剂 (insulin secretagogue)。 |
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Hansen, A.M.K., Hansen, J.B., Carr, R.D., et al.Kir6.2-dependent high-affinity repaglinide binding to β-cell KATP channelsBr. J. Pharmacol.144(4),551-557(2005)
Mark, M., and Grell, W.Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogsBr. J. Pharmacol.121(8),1597-1604(1997)